DOWNSLOPING HIGH-FREQUENCY HEARING LOSS DUE TO INNER EAR TRICELLULAR TIGHT JUNCTION DISRUPTION BY A NOVEL ILDR1 MUTATION IN THE IG-LIKE DOMAIN.

Downsloping high-frequency hearing loss due to inner ear tricellular tight junction disruption by a novel ILDR1 mutation in the Ig-like domain.

The immunoglobulin (Ig)-like domain containing receptor 1 (ILDR1) gene encodes angulin-2/ILDR1, a recently discovered tight junction protein, which forms tricellular tight junction (tTJ) structures with tricellulin and lipolysis-stimulated lipoprotein receptor (LSR) at tricellular contacts (TCs) in the inner ear.Previously reported recessive mutati

read more



Genome-wide analysis of PRR gene family uncovers their roles in circadian rhythmic changes and response to drought stress in Gossypium hirsutum L.

Background The circadian clock not only participates in regulating various stages of plant growth, development and metabolism, but confers plant environmental adaptability to stress such as drought.Pseudo-Response Regulators (PRRs) are important component of the central oscillator (the core of circadian clock) and play a significant role in plant p

read more

KNOWLEDGE OF SCHOOL TEACHERS IN SECONDARY SCHOOLS OF MUMBAI CITY REGARDING PREVENTION OF SUICIDE AMONG ADOLESCENTS

Adolescence is a period of turmoil, if not dealt with it effectively.The perplexity which adolescents face could compel them to resort to such an act which could be harmful.The academic failure, loss of loved ones during the period of adolescence can affect them seriously.They may turn to the decision of ending their lives by deliberate VCR Accesso

read more